Hybrid PET/MR in the Therapy of Cervical Cancer

Inclusion Criteria: * ≥ 18 years of age * Biopsy-proven, previously untreated squamous cell carcinoma, adenosquamous carcinoma, or adenocarcinoma of the uterine cervix * Clinically visible lesion at least FIGO stage Ib or AJCC 7th edition T1b * Scheduled to undergo standard of care PET/CT for baseline assessment of disease * Anticipated to be eligible for curative intent therapy (surgery of chemoradiation therapy) as determined by the patient's primary oncologist * If female of child-bearing potential, negative serum or urine pregnancy test ≤ 7 dats prior to first PET/MRI * Informed consent reviewed and signed Exclusion Criteria: * History of sever reaction to contrast-enhanced CT scan * Inability to tolerate MRI (e.g., inability to lie flat \> 1 hour) * Presence of pacemaker, intracranial aneurysm clip, bladder stimulator, cochlear implant or metal near eyes * Poorly controlled diabetes mellitus * Creatinine \> 1.4 mg/dL or GFR \< 30 mL/min * Body Mass Index (BMI) \> 35 * Active vaginal bleeding requiring packing and emergent radiation therapy * Pregnant or lactating female * History of a prior malignancy within past 5 years, unless disease free for ≥ 3 years * Substance abuse, medical, psychological, or social conditions that may interfere with study participation