Huaier Granule for Prevention of Disease Progression of Hepatocarcinoma After Non-radical Hepatectomy

Inclusion Criteria: 1. Age: ≥ 18 and ≤ 75 years, both male and female; 2. Non-radical hepatectomy has been performed for hepatocellular carcinoma; 3. The hepatocellular carcinoma has been confirmed by pathological examination; 4. The liver and kidney function satisfies the following conditions within 15 days after surgery (excluding day 15): aspartate aminotransferase(AST), glutamic-oxalacetic transaminase(ALT)\<3 upper limit of normal(ULN), total bilirubin ≤2 ULN, serum creatinine \<1.5 ULN; 5. Other laboratory tests meet the following requirements within 15 days after surgery (excluding day 15): Hb≥9g/dl, platelet count≥60×109/L, neutrophil count\> 1.5×109/L; 6. The expected survival time ≥12 weeks; 7. The subjects volunteer to sign the informed consent. Exclusion Criteria: 1. Non-hepatocellular carcinoma patients; 2. Those who received radical hepatectomy; 3. Those with hepatic decompensation; 4. Pregnant or lactating women; 5. Those with HIV infection or AIDS-associated diseases; 6. Those with severe acute and chronic diseases, such as infection, diabetes cardiac insufficiency, pulmonary insufficiency, renal insufficiency; 7. Those who can not take drugs by oral route; or those develop serious adverse drug reaction; 8. Drug abusers or those with psychological or mental diseases that may interfere with study compliance; 9. Conditions that are considered not suitable for this study investigators.