The primary purpose of this study is to compare the re-infection rates in patients undergoing 2-stage revision arthroplasty who receive additional oral antibiotic therapy to those patients who received in-hospital perioperative antibiotic only. Patients will be monitored for re-infection following hospital discharge, defined as deep infection of the joint space/capsule that requires return to the operating room within 24-months of the re-implantation procedure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
185
Oral Antibiotics will be prescribed for 3 months per recommendations of an infectious disease specialist.
Rush University Medical Center
Chicago, Illinois, United States
Central DuPage Hospital
Winfield, Illinois, United States
Rothman Institute
Philadelphia, Pennsylvania, United States
Vanderbilt
Nashville, Tennessee, United States
Infection Rate
Time frame: 24 months
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