Immunogenicity of Seasonal Influenza by Delivery Directly to Ileum

Inclusion Criteria: * Able and willing to complete informed consent * Healthy, as established by medical history, physical exam, and laboratory assessments * Has normal bowel movements * Willing to abstain from caffeine and xanthine containing substances for 24 hours before procedure until after discharge Exclusion Criteria: * Not able to donate up to 550 ml of blood over several months * Exposure to an investigational drug or vaccine 8 weeks prior to study * Abnormal ECG findings * History of irritable bowl or any other inflammatory gastrointestinal disorder * Any individual with increased risk for bowl obstruction * Radiation exposure above target values 50 mSv within the past 30 days or a cumulative dose above 150 mSV in the past 12 months * History of substance abuse * Subject unwilling to use an approved method of contraception during study and for 2 months after study * Positive for HCV, HIV, or HBV * Presence of implantable device that is sensitive to radio frequencies ( e.g. pacemakers) * History of autoimmune disorder, or an immunosuppressive disorder * Stool sample with occult blood at baseline * Any other medical, psychiatric, social condition, or occupation, in the judgement of the investigator is a contraindication to the compliance of the protocol or informed consent