The Safety and Immunogenicity of Haemophilus Influenzae Type b Vaccine in Different Injection Site

Inclusion Criteria: * participants were under 1 years old, and were in good healthy * participants were full-time pregnancy and birth weight were more than 2.5 kg Exclusion Criteria: * current infectious fever or acute disease * a history of hypersensitivity to study vaccine components especially tetanus toxoid * a history of allergy, autoimmune, convulsions, seizures heredity disease * a history of Hib vaccination or Hib disease * a history of congenital deformity, developmental disorders or serious chronic diseases, muscle injection contradiction, and immunosuppressive agents, hormone or immunoglobulin received.