The investigators would like to propose a prospective longitudinal observational cohort study for patients who will be diagnosed and/or treated for chronic myeloid leukemia at Asan Medical Center, Seoul, Korea, to use the acquired data for fundamentals of other retrospective analysis.
1. Acquisition of informed concent form 2. Data acquisition from medical record including * demographic / disease-associated factors * details of treatment, and its results * complications during treatment * genetic data * survival outcome (upto 30 years) 3. Accumulation of data for 30 years 4. Use of data for other retrospective analysis (including Asan Medical center Cell Banking basic data)
Study Type
OBSERVATIONAL
Enrollment
100
All patients who will be enrolled in this prospective registry are confined to those who are diagnosed as chronic myeloid leukemia at Asan Medical Center, Seoul, Korea, from Jan 2013 till Dec 2047
Asan Medical Center
Seoul, South Korea
Overall survival
Time frame: 30 years
Event-free survival
Definition of events will be as 'failure', 'progress to AP/BC', 'intolerant and medication change', and 'death from any cause'.
Time frame: 30 years
Failure-free survival
Failure will be defined as BCR-ABL elevation at 2 serial times, progression to AP/BC, loss of hematologic / cytogenetic response, any appearance of ABL kinase mutation, and clonal evolution.
Time frame: 30 years
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