This studies was designed to investigate the importance of skin type and UV-exposure on side effects after exposure to an Intense Pulsed Light Home-use device. 21 healthy subjects will receive 8 UV-exposures on one buttock and subsequently three weekly IPL-exposures.
Twenty-one healthy subjects will be exposed to UV-exposures 8 times over 3 weeks on a test-area (4 x 6cm) on one buttock to induce pigmentation. This will be followed by 3 weekly IPL (intense pulsed light) exposures. At 24 hours after the first IPL exposure, biopsies will be excised from the buttocks of the subjects (4 each).The skin will be evaluated after IPL exposure for: skin reactions, pain and mRNA expression of two pigment markers. Follow-up visits is planned at 1 and 4 weeks after the third and final IPL exposure.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
21
A light based home use device for hair removal
Bispebjerg Hospital
Copenhagen, Bispebjerg, Denmark
Changes in skin reaction development
Redness, edema, pigment changes, texture changes, blisters and crusting
Time frame: Immediately after, 1 hr after, 16-24 hrs after, 1 week and 4 weeks after IPL exposure
Pain
Time frame: Immediately after IPL exposure (approx. 2 min)
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