Comparison of the Efficacy and Safety of Closone and Clopidogrel With Aspirin

Inclusion Criteria: * Subjects under condition after Post-Percutaneous Coronary Artery Intervention over twelve months * 20\~85 years old * Willing to adhere to protocol requirements and sign a informed consent form Exclusion Criteria: * Subject who did not undergo or failed Stent Implantation * Subjects who took an anti-coagulant, anti-thrombotic regularly before the study, or plan to have continuous treatment during the study * Subjects with a history of hypersensitivity to Clopidogrel, Aspirin * Subjects with uncontrolled severe hypertension * Subjects with high risk of hemorrhage like blood coagulation disorders :gastrointestinal bleeding, gross hematuria, intraocular bleeding, hemorrhagic stroke, intracranial hemorrhage * Subjects with intractable arrhythmia, intracranial hemorrhage * Subjects with Severe cardiomyopathy (New York Heart Association(NYHA) Class Ⅳ) * Subjects with Severe hepatopathy(AST and ALT \> 10 times the upper limit of normal) * Subjects who are pregnant, breastfeeding and not using medically acceptable birth control * Subjects considered as unsuitable based on medical judgement by investigators