The purpose of this study is to provide proof-of-concept that directional stimulation, in an intraoperative setting, is perceivable in a subject and is different from omnidirectional stimulation. The tests will be performed using a dedicated DBS lead connected to external neurostimulator.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
13
Test phase will be performed intra-operatively, prior to chronic lead implant
Inselspital University Hospital
Bern, Switzerland
Measurement of the therapeutic window's boundaries when stimulating in specific angular directions, and comparison to those obtained when stimulating in all directions.
A therapeutic window is defined as the difference between the electrical current threshold at which a desired therapeutic effect is obtained and the current threshold at which side effects appear.
Time frame: up to one hour during surgery
Electrical functionality of the study device during the test phase
The electrical integrity of the device will be measured before and after its use, to confirm that it was functional throughout the test phase.
Time frame: 1 day
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