Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort)

Centre Hospitalier Universitaire Dijon1,153 enrolled

Overview

The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies. The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.

Study Type

INTERVENTIONAL

Allocation

Masking

NONE

Enrollment

1,153

Conditions

AMD Glaucoma

Interventions

Optical Coherence Tomography

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Persons who have given their written consent * Persons who are taking part in the Dijon 3C study Exclusion Criteria: * Persons who are not registered with social security agency * Persons who are unable to sit upright during a consultation

Outcomes

Primary Outcomes

Measure the mean thickness of postganglionic fibers

Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.

Time frame: T=7 years of the 3C cohort