The purpose of this study is to compare the test product Salmeterol/fluticasone Easyhaler with the reference product Seretide Diskus in terms of drug absorbed in the bloodstream.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Masking
QUADRUPLE
Enrollment
50
2 inhalations as a single dose
2 inhalations as a single dose
2 inhalations as a single dose
Orion Pharma Clinical Pharmacology Unit
Espoo, Finland
Pharmacokinetic parameter Cmax of plasma salmeterol concentration
Time frame: Within 34 h
Pharmacokinetic parameter Cmax of plasma fluticasone propionate concentration
Time frame: Within 34 h
Pharmacokinetic parameter AUCt of plasma salmeterol concentration
Time frame: within 34 h
Pharmacokinetic parameter AUCt of plasma fluticasone propionate concentration
Time frame: within 34 h
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2 inhalations as a single dose