Decoding Chronic Pain With fMRI

University of Cambridge76 enrolled

Overview

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Chronic Back Pain

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age 18-60 * pain \> 6months * right-handed * non-smoking * mechanical back pain Exclusion Criteria: * significant neurological or psychiatric disease * major systemic illness * MRI exclusion criteria

Locations (1)

Addenbrookes Hospital

Cambridge, United Kingdom

Outcomes

Primary Outcomes

Functional brain connectivity

Assessed by fMRI

Time frame: 6 months

Data from ClinicalTrials.gov

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