Study to Test the Value of a Pain Modulation Test in Predicting Persistent Postoperative Pain After Breast Cancer Surgery

University Hospital, Geneva200 enrolled

Overview

The purpose of this study is to test the hypothesis that a preoperative test of pain modulation predicts persistent pain 4 months after breast cancer surgery. In addition, a risk score for the prediction of persistent pain will be developed from parameters available before surgery.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Chronic Pain Acute Pain

Interventions

comprehensive preoperative testing for risk factors of persistent postoperative painOTHER

nociceptive reflex threshold, pain threshold, CPM-effect of hot water bath, pain sensitivity questionnaire, STAI, BDI, fear of surgical consequences

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age \>=18 years * American Society of Anesthesiology functional status I-III * able to read and understand the information sheet and give informed consent Exclusion Criteria: none

Locations (1)

Hôpitaux Universitaires de Genève

Geneva, Canton of Geneva, Switzerland

Outcomes

Primary Outcomes

prevalence of pain at the site of surgery

clinically important pain defined as either necessitating analgesic treatment or having an intensity of more than 3/10 at rest or 5/10 on movement, at 4 months after surgery

Time frame: 4 months postop

Secondary Outcomes

acute pain

maximum pain \>3/10

Time frame: 24h

subacute pain

average pain, maximum pain \>2

Time frame: 1 week

prevalence of pain necessitating analgesics at the site of surgery

Time frame: 4 months

prevalence of pain at the site of surgery

Time frame: 8 months

prevalence of pain at the site of surgery

Time frame: 12 months

Data from ClinicalTrials.gov

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