Phase-3 Study of ASP7374, Cell-culture-derived Influenza Vaccine

Inclusion Criteria: * Medically stable, as judged on the basis of history and concurrent diseases * Subject understands procedure of the protocol and is willing to comply with the protocol Exclusion Criteria: * Scheduled to receive another vaccine during the study * Received influenza HA vaccine within 180 days prior to screening * Received or scheduled to receive a live vaccine within 28 days prior to vaccination with the study vaccine, and received or scheduled to receive an inactivated vaccine or a toxoid within 7 days prior to vaccination with the study vaccine * Diagnosis of immune deficit in the past, has a family member (within the third degree of kinship) with a diagnosis of congenital immunodeficiency syndrome * Received one of the following medications or treatment prior to vaccination with the study vaccine: Interferon formulation, drugs which affect the immune system, corticosteroids, G-CSF, M-CSF, human immunoglobulin products, blood products * History of anaphylactic shock or an allergic reaction such as generalized eruption due to food or drug (including vaccines) allergies, fever ≥39.0°C within 2 days after the previous vaccination (influenza vaccine and others) * History of seizures * History of Guillain-Barre syndrome or acute disseminated encephalomyelitis (ADEM) * Confirmed diagnosis of influenza within 84 days prior to screening test * Body temperature of ≥37.5°C on Day 1 (before vaccination) * Immunological tests reveal positive HBs antigen, HCV antibody, and HIV antigen and/or antibody