Comparison of Sequencing and PNA Clamping of EGFR Gene in Patients With Non-Small Cell Type Lung Cancer

Inclusion Criteria: * Locally advanced stage IIIB not suitable for curative therapy or stage IV (metastatic) disease or relapsed NSCLC * ECOG Performance status 0\~2. * Written Informed Consent * Female or male patients aged 18 years or over, eligible for treatment for NSCLC Exclusion Criteria: * Previous exposure to EGFR-TKI * Concomitant use of other anti-cancer drugs with EGFR-TKI * Patients without available Tumor DNA * As judged by the investigator, any evidence of severe or uncontrolled systemic disease (e.g. unstable or uncompensated respiratory, cardiac, hepatic, or renal disease) * Evidence of any other significant clinical disorder or laboratory finding that makes it undesirable for the subject to participate in the study * Pregnancy or breast-feeding women (women of child¬bearing potential). Women of childbearing potential must practice acceptable methods of birth control to prevent pregnancy.