Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis

Centre Hospitalier Universitaire Dijon112 enrolled

Overview

One useful effect of early intravitreal corticotherapy is to diminish inflammatory complications after endophthalmitis, which may cause, at least in part, serious complications (retinal detachment, macular edema) which are, more than the infection, causes of the complications seen after acute endophthalmitis.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

112

Conditions

Post-operative Endophthalmitis

Interventions

Intravitreal injection of Betamethasone + antibioticsPROCEDURE

Intravitreal injection of antibioticsPROCEDURE

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * All patients male or female with no age limit * Hospitalized for the diagnosis and treatment of acute endophthalmitis following cataract surgery * Who had given their consent after being informed about intravitreal corticotherapy Exclusion Criteria: * Patients who refused or were unable to give their consent * Prior intravitreal corticotherapy

Locations (6)

CHU de Besançon

Besançon, France

CHU

Dijon, France

CHU de Grenoble

Grenoble, France

CHU de Nancy

Nancy, France

CHU de Saint Etienne

Outcomes

Primary Outcomes

Measure the evolution of visual acuity

Time frame: up to12 months

Data from ClinicalTrials.gov

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