The Influences of Caffeine on Heart Rate Variability of Preterm Infants

Rambam Health Care Campus25 enrolled

Overview

Caffeine has a stimulatory effect on the ANS. This has not yet been investigated in preterm infant who get caffeine before stopping ventilation. The investigators hypothesis is that this stimulatory effect may be characterized by HRV analysis methods.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Autonomic Nervous System

Interventions

CaffeineDRUG

Caffeine will be given according to departmental protocol

Eligibility

Sex: ALLMin age: 25 WeeksMax age: 34 Weeks

Medical Language ↔ Plain English

Inclusion Criteria: * infants born before 34 weeks gestation Exclusion Criteria: * sepsis * congenital malformations

Locations (1)

RMC

Haifa, Israel

Outcomes

Primary Outcomes

Heart rate variability

Heart rate, SD, SDNN, HF, LF, VLF, TP

Time frame: 1 hour

Data from ClinicalTrials.gov

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