The purpose of this study is to investigate the efficacy and safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with spinal cord injury
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
15
Intravenous injection of Autologous Adipose Derived Mesenchymal Stem Cells. Dose : 2x10e8 cells / 20mL Intrathecal injection of Autologous Adipose Derived Mesenchymal Stem Cells. Dose : 5x10e7 cells / 2mL Into a spinal cord injection of Autologous Adipose Derived Mesenchymal Stem Cells. Dose : 2x10e7 cells / 1mL
Korea University Anam Hospital
Seoul, South Korea
ASIA (American Spinal Injury Association) scale
To evaluate the change of treated spinal cord before cell implantation and at 3 and 6 months post injection of MSCs.
Time frame: 32 weeks
Magnetic Resonance Imaging
To evaluate the change of treated spinal cord injury using Magnetic Resonance Imaging (MRI) at 3 and 6 months post injection of MSCs.
Time frame: 32 weeks
MEP/SSEP
To evaluate the change of treated spinal cord before cell implantation and at 3 and 6 months post injection of MSCs.
Time frame: 32 weeks
ADL (activities of daily living)
To evaluate the change of treated spinal cord before cell implantation and at 3 and 6 months post injection of MSCs.
Time frame: 32 weeks
SF-36
To evaluate the change of treated spinal cord before cell implantation and at 3 and 6 months post injection of MSCs.
Time frame: 32 weeks
ODI (Oswestry Disability Questionnaire)
To evaluate the change of treated spinal cord before cell implantation and at 3 and 6 months post injection of MSCs.
Time frame: 32 weeks
Frequency of Adverse Events
Time frame: 32 weeks
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