Ventilator acquired pneumonia (VAP) are severe nosocomial infections. On the other side, bronchial fungi colonization is commonly observed in ICU; therefore, the investigators propose to study the role of bronchial fungi colonization on the occurrence of VAP taking into account the immune status of the patient and the antibiotic and antifungal treatments he has received.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
213
cutaneous, rectal, nose and mouth swabs to identify potential fungi colonization
HLA DR antigen, cytokines (IL 6 and 10), B-glucan
fungi and bacteria endotracheal aspiration
Hospital University Clermont Ferrand Gabriel Montpied
Clermont-Ferrand, France
University Hospital of Grenoble
Grenoble, France
Onset of a late ventilator acquired pneumonia (VAP)
Time frame: Participants will be followed for the duration of mechanical ventilation, an expected time frame that can go from 5 days to up to 8 weeks
Onset of a pseudomonas aeruginosa associated VAP
Time frame: Participants will be followed for the duration of mechanical ventilation, an expected time frame that can go from 5 days to up to 8 weeks
Onset of late ventilator associated pneumonia associated to staphylococcus aureus
Time frame: Participants will be followed for the duration of mechanical ventilation, an expected time frame that can go from 5 days to up to 8 weeks
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