Neurophysiological Molecular and Developmental Analysis of the Glutamate Synapse in Autism

N/ACompletedNCT01770548

University Hospital, Tours497 enrolled

Overview

Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism

Analysis about 50 genes in glutamate synapse

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Masking

NONE

Enrollment

497

Conditions

Autism

Interventions

analysis of the glutamate synapse in autismGENETIC

Neurophysiological, molecular and developmental analysis of the glutamate synapse in autism

DNA collectionGENETIC

DNA collection

Auditory evoked potentialsOTHER

auditory evoked potentials

Eligibility

Sex: ALLMin age: 2 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * have a Pervasive Developmental Disorder Exclusion Criteria: * N/A

Locations (4)

CHRU - Centre de Ressources Autisme (CRA)

Brest, France

CHS du ROUVRAY

Rouen, France

Chru - Cic

Tours, France

CHRU - Pédopsychiatrie

Tours, France

Outcomes

Primary Outcomes

screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients

Time frame: two years

Data from ClinicalTrials.gov

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