This prospective, observational study will evaluate the efficacy, safety and tolerability of RoActemra/Actemra (tocilizumab) in patients with moderate to severe active rheumatoid arthritis who have had an inadequate response or are intolerant to one or more conventional disease-modifying anti-rheumatic drugs. Data will be collected from patients initiated on RoActemra/Actemra treatment according to the local label at baseline, Weeks 4, 12 and 24, and at 3 and 6 months after the last dose of study drug.
Study Type
OBSERVATIONAL
Enrollment
100
Unnamed facility
Safat, Kuwait
Unnamed facility
Beirut, Lebanon
Unnamed facility
Beirut, Lebanon
Unnamed facility
Beirut, Lebanon
Unnamed facility
Beirut, Lebanon
Unnamed facility
Beirut, Lebanon
Unnamed facility
Byblos, Lebanon
Unnamed facility
Saida, Lebanon
Unnamed facility
Tripoli, Lebanon
Unnamed facility
Doha, Qatar
...and 2 more locations
Safety: Incidence of adverse events
Time frame: approximately 3 years
Percentage of patients achieving a clinically meaningful improvement in disease activity: DAS28 reduction of at least 1.2 units, low disease activity (DAS28 </= 3.2) or remission (DAS28 <2.6)
Time frame: approximately 3 years
Clinical/demographic patient characteristics at initiation of RoActemra/Actemra treatment
Time frame: approximately 3 years
Treatment regimens: Concomitant medications
Time frame: approximately 3 years
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