The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.
This study is performed using a multiphoton microscopy-based tomograph (MPTflex) developed by JenLab, GmbH (Germany) and a MPM imaging system developed at BLI: Fast Large Area Multiphoton Exoscope (FLAME) to image non-invasively normal and lesional skin. Skin lesions are imaged by multiphoton microscopy and images are compared to those obtained from histopathology through standard of care processed skin biopsies. Any biopsies will be performed by the health care provider as a standard of care procedure.
Study Type
OBSERVATIONAL
Enrollment
250
non-invasive optical biopsy
Beckman Laser Institute Medical Clinic
Irvine, California, United States
RECRUITINGhigh-resolution images of skin
The complementary imaging modalities (MPM, MI) will provide insights into a better understanding of the relationship between microscopic and macroscopic properties of the skin.
Time frame: up to 12 months
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