The purpose of this study is to determine whether the routine use of methylnaltrexone in the post-operative pediatric spinal fusion patient will decrease the incidence of constipation.
Methylnaltrexone will be given to pediatric patients post-operative from spinal fusion surgery on post-operative day number 3 and then again on postoperative day number 4, if no laxation achieved. Various outcome measures, safety and efficacy of the drug will be observed and recorded.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Patient will receive methylnaltrexone on postoperative day 3 on a weight based dose and again 24 hours later if required.
Standard institutional bowel protocol will begin on post-operative day 1. Miralax,Docusate sodium or senna will be given on a weight-based dosing. If no bowel movement in 72 hours, bisacodyl or magnesium hydroxide will be added.
Shriners Hospitals for Children- Spokane
Spokane, Washington, United States
reduction of post-operative opioid induced constipation
Time frame: first post-operative week
time to ambulation in post-operative pediatric spinal fusion patients
Time frame: first post-operative week
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.