Ischemic Preconditioning in Endurance Athletes

Maastricht University Medical Center29 enrolled

Overview

The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Exercise

Interventions

Remote ischemic preconditioningOTHER

Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Informed consent * Healthy * Age between 18 and 65 years * Endurance-trained (two or more training sessions per week) Exclusion Criteria: * Not applicable

Locations (1)

Maastricht University Medical Center

Maastricht, Netherlands

Outcomes

Primary Outcomes

Serum concentrations of cardiac troponins

Time frame: 6 hours, 2 hourly time intervals

Secondary Outcomes

Indices of cardiac function measured by echocardiography

Time frame: 2 hours post-exercise

Data from ClinicalTrials.gov

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