Various kinds of intermittent pneumatic compression devices (IPC) with particular ways of compression have been developed and used for prevention of deep vein thrombosis. There are still some controversies about the physiologic properties and clinical impact of numerous issues including the variety of the cuff length, inflation rate, compression sequence, compression-relaxation cycle rate, and pressure generation characteristics. This study is designed to compare clinical efficacies as well as venous hemodynamic improvements between Simultaneous bilateral compression with fixed venous refill time versus alternate compression with adjusted refill time
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
54
SMG-SNU Boramae Medical Center
Seoul, South Korea
Rate of Deep Vein Thrombosis
Computed tomographic angiography were performed on 4th postoperative days to detect deep vein thrombosis and evaluate its extent and location.
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Peak Velocity
Doppler ultrasonography were performed to measure one of the venous hemodynamic parameters to be compared. A longitudinal scans of bilateral superficial femoral veins, just distal to the confluence of the profunda femoral veins, were performed. Baseline velocity, flow pattern, and augmented flow of 11 seconds (Simultaneous compression arm) or 12 seconds (Alternate compression arm) were recorded. Under fixed state of other ultrasound scan parameters, peak velocity (PV) was measured by determination of maximum point of the augmented waveform.
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Mean Velocity
Doppler ultrasonography were performed to measure one of the venous hemodynamic parameters to be compared. A longitudinal scans of bilateral superficial femoral veins, just distal to the confluence of the profunda femoral veins, were performed. Baseline velocity, flow pattern, and augmented flow of 11 seconds (Alternate compression arm) or 12 seconds (Simultaneous compression arm) were recorded. This is an automatically measured mean value of venous flow.
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Peak Volume Flow
Doppler ultrasonography were performed to measure one of the venous hemodynamic parameters to be compared. A longitudinal scans of bilateral superficial femoral veins, just distal to the confluence of the profunda femoral veins, were performed. Baseline velocity, flow pattern, and augmented flow of 11 seconds (Simultaneous compression arm) or 12 seconds (Alternate compression arm) were recorded. Peak volume flow (PVF) was automatically calculated with 1-second interval around the PV.
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Total Volume Flow
Doppler ultrasonography were performed to measure one of the venous hemodynamic parameters to be compared. A longitudinal scans of bilateral superficial femoral veins, just distal to the confluence of the profunda femoral veins, were performed. Baseline velocity, flow pattern, and augmented flow of 11 seconds (Simultaneous compression arm) or 12 seconds (Alternate compression arm) were recorded. Total volume flow (TVF) was automatically calculated by the software.
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Expelled Total Volume
Expelled volume was theoretically calculated value in order to figure out how much blood was squeezed by the compression for an hour; expelled total volume (ETV) = single cycle augmented TVF x cycling rate (cycles/hour).
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Expelled Peak Volume
Expelled volume was theoretically calculated value in order to figure out how much blood was squeezed by the compression for an hour; expelled peak volume (EPV) = single cycle augmented PVF x cycling rate (cycles/hour).
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Augmented PV
Enhanced peak velocity by application of intermittent pneumatic compression
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Augmented MV
Enhanced mean velocity by application of pneumatic compression
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Augmented PVF
Enhanced peak volume flow by application of pneumatic compression
Time frame: On 4th postoperative days after total knee replacement arthroplasty
Augmented TVF
Enhanced total volume flow by application of pneumatic compression
Time frame: on 4th postoperative day after total knee replacement arthroplasty
Cycling Rate
Number of cuff inflation-deflation cycle during an hour. In group SF, the cycling rate is fixed as 90 cycles/hour, but in group AA, it is variable according to the individual venous refill time.
Time frame: on 4th postoperative day after total knee replacement arthroplasty
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.