1. MAIN OBJECTIVE : To assess the consequences of a maternal hyperthyroïd during pregnancy on intellectual development of the child from 6 to 9 years 2. SECONDARY OBJECTIVES : 1. To assess the consequences of a maternal hyperthyroïd during pregnancy on the capacities of attention, learning process and the degree of hyperactivity of the child from 6 to 9 years. 2. To study if it exist differences of intellectual development, capacities of attention, learning process, and degree of hyperactivity in the child from 6 to 9 years, born to hyperthyroid mother during pregnancy, according to: * the etiology of the maternal hyperthyroïd (transitory gestation hyperthyroid versus disease of Basedow), * the use or not of a anti-thyroid treatment, * the rate of TSH néonatal (measured with the blotter by tracking with J3 at all the new born ones).
1. INCLUSION CRITERIA : * Old from 6 to 9 years included * Age of gestation between ≥37 and \<41 weeks of amenorrhoea * Born from a mono-foetale pregnancy * Euthyroïd at the time of the entry in the study * Provided education for at the elementary school on a level adapted to its age 2. NON INCLUSION CRITERIA : * Presenting a congenital hypothyroïd or a known thyroid dysfonction at the time of the entry in the study * Carrier of a chronic pathology (organic or psychological) or malformative severe * Presenting an antecedent of Deficit of the Attention-Hyperactivity to the 1st degree 3. EXCLUSION CRITERIA : o Discovered of a thyroid dysfonction at the time of the entry in the study 4. STRATEGIES / PROCEDURES : Multicentric, comparative study of a troop of child born to hyperthyroïd mothers during pregnancy (children exposed to the maternal hyperthyroïd) and children born to euthyroïd mothers during pregnancy (nonexposed children with the maternal hyperthyroïd). * 1st part of the study: Retrospective analyze of the files of symptomatic hyperthyroid mothers during pregnancy. * 2nd part of the study: Assessment of intellectual development, capacities of attention, learning process and degree of hyperactivity of the children between 6 and 9 years. The exposed children (born to hyperthyroïd mothers during pregnancy) will be compared with nonexposed children (born to euthyroïd mothers during pregnancy).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
252
University Hospital of Amiens
Amiens, France
RECRUITINGUniversity Hospital of Angers
Angers, France
RECRUITINGCivil Hospices of Lyon
Bron, France
RECRUITINGUniversity Hospital of Kremlin Bicetre
Le Kremlin-Bicêtre, France
RECRUITINGUniversity Hospital of Lille
Lille, France
ACTIVE_NOT_RECRUITINGUniversity Hospital of Marseille
Marseille, France
ACTIVE_NOT_RECRUITINGUniversity Hospital of Nantes
Nantes, France
RECRUITINGHospital of Saint Antoine
Paris, France
RECRUITINGUniversity Hospital of Cochin
Paris, France
ACTIVE_NOT_RECRUITINGUniversity Hospital of Poitiers
Poitiers, France
RECRUITING...and 3 more locations
Scores of global development Quotient (WISC-R)
Time frame: within the first 30 days after inclusion of the patient
Score of the Achenbach Child Behavior Checklist
Time frame: within the first 30 days after inclusion of the patient
Score of the conners scale
Time frame: within the first 30 days after inclusion of the patient
Score of the Wechsler Intelligence Scale for Children (WISC-IV)
Time frame: within the first 30 days after inclusion of the patient
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