MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Cukurova University

Overview

Background: Genetics is suggested to play a critical role in the development of Behçet's disease (BD). Shared phenotypic features requires an approach to the differential diagnosis from periodic febrile syndromes particularly from mevalonate kinase deficiency related diseases. We planned to study for evaluating the frequency of mutations and their clinical significance in mevalonate kinase gene in Turkish patients with Behçet's disease.

Study Type

OBSERVATIONAL

Conditions

Behçet's Disease

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Behçet patients Exclusion Criteria: * Diagnosis of periodic fever syndromes

Locations (2)

Cukurova University

Adana, Turkey (Türkiye)

Didem Arslan Tas

Adana, Turkey (Türkiye)

Outcomes

Primary Outcomes

Frequency of mevalonate kinase frequency in Behçet disease

Time frame: One year

Secondary Outcomes

Mevalonate kinase gene and clinical correlations in Behçet's disease

Time frame: One year

Data from ClinicalTrials.gov

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