Cancer-related fatigue is one of the most common and distressing symptoms associated with a cancer diagnosis.Fatigue related to cancer often appears before a diagnosis, worsens during treatment, and lasts for years after treatment in up to 35% of patients. Despite the long-term effects of cancer-related fatigue, the treatment options available are not always appropriate or helpful for all patients.Light therapy is an effective treatment for other disorders related to fatigue. The purpose of the study is to investigate the role of light therapy on quality of life, sleep patterns, and physical measures of immune function and stress hormones in individuals with post-treatment cancer-related fatigue.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
88
Behavioural Medicine Laboratory
Calgary, Alberta, Canada
Change in fatigue symptoms from baseline to post-treatment
Time frame: Baseline, after each treatment week (each week for 4 weeks), and at week 5
Change in objective measures of sleep using wrist actigraphy from baseline to post-treatment
Time frame: Baseline (for 7 days), week 5 (for 7 days)
Change in subjective measures of sleep using sleep diaries from baseline to post-treatment
Time frame: Baseline (for 7 days), week 5 (for 7 days)
Change in Pittsburgh Sleep Quality Index scores from baseline to post-treatment
Time frame: Baseline, week 5
Change in Profile of Mood States scores from baseline to post-treatment
Time frame: Baseline, week 5
Change in Functional Assessment of Cancer Therapy (General & Fatigue) scores from baseline to post-treatment
Time frame: Baseline, week 5
Change in salivary cortisol from baseline to post-treatment
Time frame: Baseline (for 3 days), week 5 (for 3 days)
Change in inflammatory cytokines from baseline to post-treatment
Time frame: Baseline, week 5
Change in Insomnia Severity Index scores from baseline to post-treatment
Time frame: Baseline, week 3, week 5
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