The purpose of this study is to reveal the specific effects of computer-aided cognitive training on cerebral reorganization in schizophrenia
Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing. The other training focus on facial affect discrimination and working memory. Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
80
Computer aided cognitive program designed for intensive training of auditory perception, memory and attention
Computer-aided cognitive program designed for intensive training of facial affect discrimination, memory and attention
standard treatment protocol of schizophrenia ward
University of Konstanz
Konstanz, Baden-Wurttemberg, Germany
change from baseline at post-intervention (4-weeks) and 3-months in each to the primary outcome measures: neuropsychological test scores (MCCB), MEG alpha oscillations
Time frame: baseline, post-intervention (after 4 weeks), 3-months follow-up
change from baseline in global functioning (GAF score) at 4 weeks and 3 months
Time frame: baseline, post-intervention, 3-months follow-up
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