Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

University of Konstanz20 enrolled

Overview

The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.

Study Type

INTERVENTIONAL

Allocation

Purpose

PREVENTION

Masking

NONE

Enrollment

Conditions

Psychosis

Interventions

Brain Fitness Training, Posit Science SFBEHAVIORAL

Computer aided cognitive training based on principles of neuroplasticity

Eligibility

Sex: ALLMin age: 17 YearsMax age: 37 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Early Onset Psychosis Exclusion Criteria: * Chronicity * Insufficient German skills

Locations (1)

University Konstanz

Konstanz, Baden-Wurttemberg, Germany

Outcomes

Primary Outcomes

change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activity

Time frame: baseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up

Secondary Outcomes

change from baseline in GAF score at 3-months and 7-moths follow-up

Time frame: baseline, 3-months follow-up, 7-months follow-up

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.