Frequency of Residual Neuromuscular Blockade in the Pediatric Population

Nationwide Children's Hospital5 enrolled

Overview

This study is designed to investigate the frequency of Residual Neuromuscular Blockade (RNMB) in the pediatric population.

The proposed study will be the first to investigate the incidence of residual postoperative neuromuscular blockade in the pediatric patient following the intraoperative use of NMBA's. If there is significant residual blockade present, it may be that these effects will lead to postoperative respiratory complications including hypoxemia, atelectasis, and prolonged oxygen requirement resulting in a prolonged stay in the post-anesthesia care unit.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Neuromuscular Blockade

Interventions

Neuromuscular blockadePROCEDURE

Eligibility

Sex: ALLMax age: 17 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Age less than 18 years. 2. Surgery requiring the administration of neuromuscular blocking, agents with planned extubation in the postoperative care unit (PACU). Exclusion Criteria: 1. Neuromuscular diseases which may prolong the duration of NMBA's or exaggerate the effects of residual blockade. 2. The need for postoperative mechanical ventilation. 3. Direct admission to the Pediatric ICU, NICU or CTICU.

Locations (1)

Nationwide Children's

Columbus, Ohio, United States

Outcomes

Primary Outcomes

train-of-four (TOF) ratio

TOF ratio shows the residual of neuromuscular agents.

Time frame: 1 day

Data from ClinicalTrials.gov

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