This observational study will evaluate the efficacy and safety of Avastin (bevacizumab) in combination with fluoropyrimidine-based chemotherapy in elderly patients (\>/= 65 years of age) with newly diagnosed metastatic colorectal cancer. Patients will be followed until disease progression, death, withdrawal of consent, discontinuation of physician-patient relationship or study closure, whichever comes first.
Study Type
OBSERVATIONAL
Enrollment
3
Unnamed facility
Budapest, Hungary
Median progression-free survival
Time frame: approximately 3.5 years
Overall response rate (complete response + partial response)
Time frame: approximately 3.5 years
Clinical benefit rate (complete response + partial response + stable disease)
Time frame: approximately 3.5 years
Metastasectomy rate
Time frame: approximately 3.5 years
Mean duration of Avastin treatment
Time frame: approximately 3.5 years
Safety: Incidence of adverse events
Time frame: approximately 3.5 years
Median progression-free survival in subgroup receiving Avastin plus fluorouracil monotherapy
Time frame: approximately 3.5 years
Median progression-free survival according to age group (65-74 years; >/= 75 years)
Time frame: approximately 3.5 years
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