Impact of Clomiphene Citrate Administration During the Early Luteal Phase on Endocrine Profile in IVF Cycles

Fundació Privada Eugin10 enrolled

Overview

The purpose of this study is to evaluate the effect on LH levels of the 5-day CC administration during luteal phase in oocyte donors, to investigate whether the CC corrects the suppressed LH levels in the luteal phase and whether it prolongs the luteal phase in the agonist triggered antagonist cycles.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

NONE

Enrollment

Conditions

Female Infertility

Interventions

Clomifene CitrateDRUG

Clomiphene citrate 100 mg daily for 5 days

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Oocyte donors * 18-35 years old * BMI 18-29 Kg/m2 * Normal basal hormonal levels * No contraceptive pill Exclusion Criteria: * Polycystic ovarian syndrome (PCOS) * Previous participation in the study

Locations (1)

Clínica EUGIN

Barcelona, Barcelona, Spain

Outcomes

Primary Outcomes

LH Levels (IU)

Time frame: Luteal phase (up to 2 weeks)

Secondary Outcomes

Endometrial development (Noyes criteria)

Time frame: Luteal phase (1 day)

Data from ClinicalTrials.gov

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