One of the aim of the neurosurgical treatment of brain tumor is to offer the maximal resection with the minimal neurological risk. The presurgical mapping of eloquent areas with functional magnetic resonance imaging (fMRI) is helpful to plan the surgery. BOLD fMRI is now the gold standard to map language areas. However, BOLD signal is diminished near the brain tumor. It is now possible to detect cortical activation with arterial spin labeling (ASL) techniques, detecting variations of perfusion during an activation paradigm (fASL), fASL could be interesting to detect eloquent areas near a brain tumor.
Study Type
OBSERVATIONAL
Enrollment
34
Rennes University Hospital
Rennes, France
Qualitative and quantitative comparison of brain activations obtained with both techniques (BOLD fMRI and fASL)
Qualitative and quantitative comparison of brain activations obtained with both techniques (BOLD fMRI and fASL) to presurgically detect language areas located near a brain tumor
Time frame: 2 years
Langage laterality index obtained with both techniques (BOLD fMRI and fASL)and fASL)
Size and location of activations obtained with BOLD fMRI and fASL in the presurgical detection of language areas
Time frame: 2 years
Difference of cerebral blood flow maps obtained with ASL and fASL
Cerebral blood flow quantification obtained with standard ASL and extracted from fASL
Time frame: 2 years
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