Efficacy of Socket Grafting for Alveolar Ridge Preservation

Inclusion Criteria: * Age: 18 to 75 years. * Gender: No restriction. * Subjects must require a single-rooted tooth extraction (Tooth deemed as periodontally and/or restoratively hopeless), except lower incisors and second premolars. * Subjects must be able and willing to follow instructions related to the study procedures. * Subjects must have read, understood and signed an informed consent form. Exclusion Criteria: * Reported allergy or hypersensitivity to any of the products to be used in the study. * Severe hematologic disorders, such as hemophilia or leukemia. * Active severe infectious diseases that may compromise normal healing. * Liver or kidney dysfunction/failure. * Currently under cancer treatment or within 18 months from completion of radio- or chemotherapy. * Subjects who have a long-term history of oral bisphosphonate use (i.e. 10 years or more). * Subjects with a history of IV bisphosphonates. * Subjects with uncontrolled diabetes. * Subjects with severe metabolic bone diseases, such as Paget's disease of bone, will be excluded. * Pregnant women or nursing mothers. * Smokers: Subjects who have smoked within 6 months of study onset. * Concomitant medications: Subjects on concomitant drug therapy for systemic conditions that may affect the outcomes of the study will not be included in the study. NOTE: Occasional, short-term use (7-14 days) of analgesics or common cold medications is permitted. Use of such medications will be reviewed and recorded by the investigator. \- Any other non-specified reason that from the point of views of the investigators will make a candidate not a suitable subject for the study (e.g. limited mouth opening).