Prediction of Hemodynamic Reactivity During Suspension Laryngoscopy Using Analgesia/Nociception Index (ANI)

Emmanuel Boselli50 enrolled

Overview

The aim of this study is to evaluate the performance of Analgesia/Nociception Index for the prediction of hemodynamic reactivity in adult patients undergoing suspension laryngoscopy on general anesthesia.

Measurement of analgesia/nociception index at different time points during procedure and assessment of analgesia/nociception index to predict hemodynamic reactivity by building receiver observer's characteristic curve.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Anesthesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-75 years * Suspension laryngoscopy for diagnostic or therapeutic purposes * Total intravenous anesthesia using propofol and remifentanil Exclusion Criteria: * age \<18 yrs or \>75 yrs * arrythmia * administration of anticholinergic drugs or neuromuscular blockade reversal in the 20 previous minutes * psychiatric diseases * autonomic nervous system disorders (epilepsy)

Locations (1)

Hôpital Édouard Herriot, HCL

Lyon, Rhône, France

Outcomes

Primary Outcomes

Change in heart rate and/or systolic blood pressure by more than 20% within 5 minutes

Time frame: Before induction of anesthesia, 1 min after beginning of procedure, at steady-state anesthesia during procedure (an expected average of 10 min) and at arousal from general anesthesia in the end of procedure (an expected average of 20 min)

Data from ClinicalTrials.gov

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