We will conduct a cluster randomized controlled trial to compare two antibiotic pre-authorization strategies (Fellow-based vs. Pharmacist-based). We believe that amount and duration of antibiotic consumption would be lower in the pharmacist group while the clinical outcome would be equivalent between two groups.
Study design: A cluster randomized controlled trial Settings: 6 general medical wards at Siriraj Hospital, Bangkok, Thailand
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
984
All prescriptions of controlled antibiotics (Piperacillin/Tazobactam, Imipenem/Cilastatin, Meropenem and Doripenem) can be freely prescribed for the first 72 hours. After that, the prescription requires approval. Antibiotic preauthorization program will be operated by ID-fellows, under the supervision of ID staffs.
All prescriptions of controlled antibiotics (Piperacillin/Tazobactam, Imipenem/Cilastatin, Meropenem and Doripenem) can be freely prescribed for the first 72 hours. After that, the prescription requires approval. Antibiotic preauthorization program will be operated by general pharmacists, under the supervision of ID staffs.
Siriraj Hospital
Bangkok, Bangkok, Thailand
Defined Daily Dose (DDD) of antibiotics
DDD of antibiotic use for that given infection (all antibiotics and controlled antibiotics)
Time frame: Participants will be followed for the total duration of antibiotic therapy for that given infection, an expected average of 2 weeks
Total duration of antibiotic use
Total duration of antibiotic use for that given infection (all antibiotics and controlled antibiotics)
Time frame: Participants will be followed for the total duration of antibiotic therapy for that given infection, an expected average of 2 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.