Increased intra-abdominal pressure (IAP) affects pulmonary dynamics. However, little is studied whether pulmonary dynamics affects IAP. We hypothesize that the change of IAP can also reflect the change of pulmonary dynamics. In this study, we choose patients who received spontaneous breathing trial to answer the hypothesis.
During the weaning process, we tapered down the respiratory support from mechanical ventilation and recruited respiratory muscles to work. Previous study showed that transdiaphragmatic pressure was increasing while pressure support was reducing. However, the transdiaphragmatic pressure required invasive procedure to measure and not used frequently in weaning. IAP reflects the pleural pressure. If the PEEP is not changed, change of IAP is largely due to change of transpulmonary pressure. Study Aim: 1. To evaluate the patterns of change of IAP during SBT 2. To predict success of SBT by the change of IAP 3. To predict weaning outcome by the change of IAP
Study Type
OBSERVATIONAL
Enrollment
100
Nin-Chieh Hsu
Taipei, Taipei, Taiwan
NOT_YET_RECRUITINGNational Taiwan University Hospital
Taipei, Taiwan
RECRUITINGTo evaluate the patterns of change of IAP during SBT
30min, 60min, 120min during a 2-hr SBT
Time frame: 30min, 60min, 120min
To predict success of SBT by the change of IAP
To predict success of 2-hour IAP the change of IAP between 0 min and 30 min, and tha change of IAP beween 0 min and 120 min
Time frame: 0 min, 30 min, 120 min
To predict weaning success by the change of IAP
To predict weaning success by the change of IAP between 0 min and 30 min, and tha change of IAP beween 0 min and 120 min
Time frame: 0 min, 30 min, 120 min
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