The iatrogenic induction of local endometrial injury caused through hysteroscopy or pipelle sampling in the preceding non- transfer cycle improves the IVF outcome parameters in patients with previous IVF failures.
Endometrial injury was preformed either through hysteroscope during office hysteroscopy through the non touch technique or through pipelle biopsy in the early follicular phase (days 5 to 9) in the preceding cycle of the IVF treatment.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Assisted Reproduction Unit 3rd Department of Obstetrics & Gynecology, Attikon University Hospital
Athens, Attica, Greece
Assisted Reproduction Unit
Alexandroupoli, Thrace, Greece
positive bHCG rate
Time frame: through study completion, an average of 2 years
clinical pregnancy rate
Time frame: 2 years
live birth rate
Time frame: 2 years
Ectopic pregnancy rate
Time frame: 2 years
Miscarriage rate
Time frame: 2 years
Ongoing pregnancy rate
Time frame: 2 years
Pregnancy complications (preterm birth, placental abnormalities, bleeding throughout pregnancy, pregnancy related hypertensive disorders, IUGR and SGA)
Time frame: 2 years
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