Role of Proteomics and Metallomics in Cerebral Vasospasm Following Subarachnoid Hemorrhage

State University of New York - Upstate Medical University40 enrolled

Overview

The purpose of this study is to determine the role of Proteomics and Metallomics in Cerebral Vasospasm following Subarachnoid Hemorrhage

Study Type

OBSERVATIONAL

Enrollment

Conditions

Subarachnoid Hemorrhage Cerebral Vasospasm Hydrocephalus

Eligibility

Sex: ALLMin age: 18 YearsMax age: 89 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Non traumatic SAH documented by CT scan * Patient with SAH who would need external ventricular drain (EVD) for the management of hydrocephalus * Patients with normal pressure Hydrocephalus that require an external drain * Control (non - hemorrhagic) group - CSF collected from patients with posterior fossa tumor or stroke with EVD in place for the management of hydrocephalus. Exclusion Criteria: * Recent infection within last 1 month of presentation- can increase inflammatory markers * Recent surgery or acute myocardial infarction within last 1 month of presentation * Age \> 89 years or \< 18 years

Locations (1)

State University of New York Upstate Medical University

Syracuse, New York, United States

Outcomes

Primary Outcomes

Protein identification and concentration

Time frame: For the duration of CSF drainage, or until the 21st day after admission.

Metal ion identification and concentration

Time frame: For the duration of CSF drainage, or until the 21st day after admission.

Data from ClinicalTrials.gov

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