EtCO2 Monitoring in Acute Self-poisoning

University Hospital, Grenoble200 enrolled

Overview

There is no consensus on monitoring criteria in acute self poisoning. Clinical scores, vital signs or lactatemia have failed to prove good predictive value. The main acute self poisoning complication is decreased consciousness level with consequent increased risk of hypoxemia and aspiration pneumonitis. Several clinical studies have recently shown that EtCO2 monitoring can be valuable in procedural sedation in the emergency department. It is able to predict hypoxemia before any SaO2 decrease and any complications related to these procedures. We therefore hypothesized that EtCO2 could help in acute self poisoning patients' monitoring in the ED.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Acute Intentional Overdose

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * \>18y/o * acute self poisoning patients * patients requiring monitoring according to physician's opinion * patients not requiring invasive ventilation at ED admission Exclusion Criteria: * Pregnant woman * patients deprived of liberty

Locations (1)

Genoble university hospital

Grenoble, France

RECRUITING

Outcomes

Primary Outcomes

ROC curve of maximal EtCO2 to predict poisoning complication

Poisoning complications are defined as: Hypoxia (Spo2\<93%) and/or Respiratory rate \<10/min or \>25/min and/or ICU admission and/or Oro tracheal intubation

Time frame: During the first 2 hours of ED admission

Data from ClinicalTrials.gov

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