Silicon Phthalocyanine 4 and Photodynamic Therapy in Stage IA-IIA Cutaneous T-Cell Non-Hodgkin Lymphoma

Inclusion Criteria: * Diagnosed with early stage MF (CTCL stage IA-IIA) * Has at least 2 evaluable plaques * Has been off systemic therapies for at least 4 weeks * Has been off topical therapies for at least 2 weeks * Has been off phototherapies for at least 2 weeks * All skin photo-types will be included * Subjects must have the ability to understand and the willingness to sign a written informed consent form * Women of child-bearing potential must agree to utilize a birth control which results in a failure rate of less that 1% per year during the study; accepted forms of birth control for this study include: injections such as Depo-Provera and Lunelle, implants such as Norplant, and intra-uterine devices * Sexually active males must agree to use a medically acceptable form of birth control for the duration of the study and for at least 3 months after the last dose of the study medication; appropriate birth control methods are using a condom with a spermicide or surgical sterilization Exclusion Criteria: * Active history of photosensitivity (e.g. xeroderma pigmentosum, lupus erythematosus, porphyria, severe polymorphous light eruption, solar urticaria) * Any medical condition that could be aggravated or may cause extreme discomfort during the study period * Lesions only on the face, scalp or other sites that would make biopsies not cosmetically acceptable * Women of childbearing potential who are pregnant or attempting to become pregnant are excluded from this study * History of allergic reactions attributed to compounds of similar chemical or biologic composition to silicon phthalocyanine (Pc 4) or other agents used in this study * Patients with uncontrolled intercurrent illness including, but not limited to ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements