Calorimetry, Insulin Resistance and Energy Metabolism Study to Understand the Risk of Obesity in Kidney Transplanted Patients

Inclusion Criteria: * Male patient, affiliated to a social security system * Aged 35 to 65 years * Renal transplant for more than a year and less than 6 years * Treated by anticalcineurin * Patient stopped all treatment with corticosteroids for more than 3 months * Patient with stable renal function defined by a calculated creatinine clearance between 30 and 90 mL/min/1, 73m according to the Cockcroft and Gault * Written informed consent after detailed explanation of the protocol. * Increase in body weight of at least 3kg during the two years prior to the inclusion of 10 patients. Stable or increasing weight less than 1kg for 10 other patients. * HIV and HCV serology negative Exclusion Criteria: * Female patients * Diabetic (type 1 or type 2) before transplantation or patients who developed diabetes after transplantation and requiring anti-diabetic treatment at the time of inclusion * Obese patient at the time of transplantation, as defined by a body mass index\> 30% * Multiple kidney transplant or other organ transplant the kidney * Patient with lower limb edema, congestive heart failure, and/or uncontrolled hypertension. * Patient with a change in body weight\> 3 kg in the last 3 months * Patient with an infection 3 months before inclusion * Subjects infected with hepatitis B, hepatitis C virus or human immunodeficiency * Patient with acute rejection within 3 months prior to inclusion * Patient not treated by anticalcineurin * Patient with a modification of immunosuppressive therapy within 3 months prior to inclusion * Patient with unstable psychiatric condition * Patient smoking\> 5 cigarettes / day * Alcoholic patient (unweaned) * Patient with stage 4 renal failure (\<30 mL/min/1, 73m ²) and stage 5 (\<15 mL/min/1, 73m ²) * hemodialysis patient * Patient with acute renal failure defined by a 25% increase in creatinine within 3 months prior to inclusion * Person under guardianship or not subject to social security * Person in period Exclusion File National Healthy Volunteers * Person who refuses to give his written consent to participation