Non-invasive Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia

Charite University, Berlin, Germany30 enrolled

Overview

The current study investigates the basic principles that underlie the efficacy of transcranial direct current stimulation for chronic auditory verbal hallucinations in schizophrenia in a multimodal design.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Auditory Verbal Hallucinations Schizophrenia

Interventions

tDCSDEVICE

active vs. sham tDCS left hemisphere

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of schizophrenia * chronic auditory verbal hallucinations * right-handed Exclusion Criteria: * drug abuse other than nicotine * severe cognitive deficits * severe medical conditions * severe neurological disorders * severe microangiopathy * history of electroconvulsive therapy * pregnancy or lactation

Locations (2)

Charité University Medicine

Berlin, Germany

Charité University Medicine

Berlin, Germany

Outcomes

Primary Outcomes

Change of Auditory Hallucination Rating Scale score

Auditory Hallucination Rating Scale score will be assessed at baseline; changes thereof at 3 days after intervention and 3 months after intervention are primary outcome measures

Time frame: baseline; 3 days after intervention; 3 months after intervention

Secondary Outcomes

Positive And Negative Syndrome Scale

Positive And Negative Syndrome Scale score will be assessed at baseline; changes thereof at 3 days after intervention and 3 months after intervention are secondary outcome measures

Time frame: baseline; 3 days after intervention; 3 months after intervention

Data from ClinicalTrials.gov

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