Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing

Deutsches Herzzentrum Muenchen70 enrolled

Overview

Unnecessary right ventricular pacing has been shown to be detrimental in recipients of implantable pacemaker or defibrillators. The ADVANTAGE study evaluates the efficacy of two pacemaker based algorithms (atrioventricular hysteresis function versus mode switch to atrial pacing) to reduce right ventricular pacing.

Comparison of the effect of an atrioventricular hysteresis function with a mode switch to atrial pacing on the right ventricular pacing percentage in a multi-centre, prospective, randomized, single blinded, cross-over study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Pacemaker Implantation for Sinus Node Disease

Interventions

pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis functionOTHER

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: Indication for the implantation of a dual-chamber pacemaker Exclusion Criteria: Persistent or permanent atrial tachyarrhythmias atrioventricular block 2nd or 3rd degree indication or the implantation of an defibrillator

Locations (3)

Klinikum Bamberg

Bamberg, Bavaria, Germany

Deutsches Herzzentrum München, Klinik für Herz- und Kreislauferkrankungen

München, Bavaria, Germany

Krankenhaus Peißenberg

Peißenberg, Bavaria, Germany

Outcomes

Primary Outcomes

Right ventricular pacing percentage

Time frame: 3 months

Secondary Outcomes

BNP levels

Time frame: 3 months

Data from ClinicalTrials.gov

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