Efficacy and Safety of Biocellulose Sheet Containing Anti-hyperpigmentation Agent ("Biocellulose Mask", "Farhorm®") in Patients Receiving Laser Treatment

Chulalongkorn University30 enrolled

Overview

The laser areas treated with biocellulose sheet from coconut juice containing anti-hyperpigmentation agent ("biocellulose mask", "Farhorm®") heal faster than vaseline ointment which is a standard treatment.

Volar surface at upper arm (2X2 cm) on both sides were treated with semi ablative, 1,550 nm Erbium: glass fractional laser. Biocellulose sheet from coconut juice containing anti-hyperpigmentation agent ("biocellulose mask","Farhorm®")was applied for 20 min on one side and the other side was treated with vaseline ointment. The redness, skin hydration and skin pigmentation were evaluated at that area before laser, immediately after laser and after applying the treatment. These parameters were compared between treatment (area treated with Biocellulose sheet from coconut juice containing anti-hyperpigmentation agent, "biocellulose mask", "Farhorm®") and control (vaseline ointment).

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Skin Pigmentation Skin Irritation

Interventions

"Biocellulose Mask", Farhorm®"DEVICE

Eligibility

Sex: ALLMin age: 20 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age 20-50 years old * No skin problem such as inflammation, fresh wounds * Not receive laser treatment during last 3 months * No history of smoking or alcohol drinking * No allergy to licorice extract, Vit C, Vit E, arbutin or stearyl glycyrrhetinate * Willing to participate in this study and can comply with study protocol Exclusion Criteria: * Has history of hyperallergic reaction * Has wound(s) on face during last 4 weeks * Has history of eczema, psoriasis during last 6 months * Has laser treatment during last month * Use steroid, antibiotic, anti-inflammatory drugs or antihistamine during 3 days before recruiting * Had major surgery during last 12 months * Has history of cancer during last 12 months * Pregnant or lactation

Locations (1)

Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Chulalongkorn Unviersity

Bangkok, Bangkok, Thailand

Outcomes

Primary Outcomes

The skin pigmentation immediately after laser therapy and after using biocellulose mask

Time frame: Change from immediately after laser treatment and 30 min after laser and treatment with mask

Data from ClinicalTrials.gov

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