Efficacy Study of Antiemetics to Reduce Postoperative Nausea and Vomiting

Seoul National University Hospital96 enrolled

Overview

We randomized patients who received laparoscopic surgery for benign gynecologic disease into double dose (Experimental Group) or single dose (Control Group) of antiemetics. We compared the degree of postoperative nausea and vomiting in experimental and control groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Postoperative Nausea and Vomiting

Interventions

RamosetronDRUG

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * Laparoscopy for benign gynecologic disease Exclusion Criteria: * Vomiting within 24 hours before surgery * Not using patient controlled analgesics postoperatively

Locations (1)

Seoul National University Bundang Hospital

Seongnam-si, Gyeonggi-do, South Korea

Outcomes

Primary Outcomes

Complete Response Rate

The percentage of patients who experienced neither nausea nor vomiting within 24 hours after surgery

Time frame: Postoperative 24 hours

Data from ClinicalTrials.gov

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