Study, the inclusion of very low birth weight premature infants followed in Dr.Sami Ulus Maternity and Children Training and Research Hospital, Department of Neonatology; be randomized to very low birth weight premature infants began eating until you are discharged from the hospital once a day to feed a group+ 900 mg of 5 billion active Bifidobacterium lactis, the addition of chicory inulin, in the other group given placebo; Patients taking weekly blood cultures, the presence of residues in both groups during feeding, to evaluate the incidence of NEC and sepsis are planned. Randomization and the number of patients planned to separate into groups.
Patients separated into four groups using the sealed envelope method.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
400
5 billion active Bifidobacterium lactis
5 billion Bifidobacterium lactis plus 900 mg İnülin per day will be given
Maltodextrin
900 mg inulin per day will be given
Şevket Yılmaz Research Hospital
Bursa, Turkey (Türkiye)
RECRUITINGDiyarbakır Research Hospital
Diyarbakır, Turkey (Türkiye)
RECRUITINGOkmeydani Research Hospital
Istanbul, Turkey (Türkiye)
RECRUITINGUmraniye Research Hospital
Istanbul, Turkey (Türkiye)
RECRUITINGNecrotizing enterocolitis
Developing of \>= grade 2 necrotizing enterocolitis suggested by radiological investigation
Time frame: 8 weeks
length of hospital stay
length of hospital stay
Time frame: 16 weeks
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