This study will assess the serum uric acid lowering effects and safety of lesinurad in combination with allopurinol over a long-term timeframe.
This is a Phase 3 extension study to assess the long-term efficacy and safety of lesinurad in combination with allopurinol in subjects who completed the double-blind treatment period in Studies RDEA594-301 and RDEA594-302.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
717
Proportion of subjects with an sUA level that is < 6.0 mg/dL
Time frame: up to a total of 5 years
Resolution of at least 1 target tophi
Time frame: Up to Month 12
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Unnamed facility
Birmingham, Alabama, United States
Unnamed facility
Birmingham, Alabama, United States
Unnamed facility
Birmingham, Alabama, United States
Unnamed facility
Gulf Shores, Alabama, United States
Unnamed facility
Pinson, Alabama, United States
Unnamed facility
Glendale, Arizona, United States
Unnamed facility
Mesa, Arizona, United States
Unnamed facility
Peoria, Arizona, United States
Unnamed facility
Little Rock, Arkansas, United States
Unnamed facility
Little Rock, Arkansas, United States
...and 197 more locations