Stem Cells Treatment for Bilateral Limbic Associated Keratopathy (HULPOFT)

Inclusion Criteria: 1. -Signed informed consent 2. -Previously diagnosed bilateral limbic obstruction 3. -Men and women over 18 years old. Good general state of health according to the findings of the clinical history and the physical examination 4. -Suffering chronic keratopathy accomplishing the following criteria: * Confirmed limbic obstruction with an impression cytology * Repeated usual treatment failure for this pathology Exclusion Criteria: 1. -Having suffered a neoplasia in the previous 5 years 2. -Local anesthesia allergies 3. -Patients having participate in any other study in the previous 90 days to the inclusion 4. -Patients on medication with tacrolimus or cyclosporine in the 4 previous week to the cellular therapy 5. -Any medical or psychiatric illness that, in the investigator opinion, could suppose a reason for the study exclusion 6. -Patients with any type of medical or psychiatric disease which, in the opinion of the investigator, could be grounds for exclusion from study 7. -Patients with congenital or acquired immunodeficiencies. HIV, HBV, HCV or treponema infection, whether active or latent 8. -Patients who have suffering major surgery or severe trauma in the prior 6 months 9. -Pregnant or breastfeeding women